Cholesterol Support

What it is

Bergamot is a citrus fruit grown primarily in southern Italy. Its extract contains unique polyphenols — including brutieridin and melitidin — not found in other citrus fruits. These compounds have structural similarities to statins.

What it does

Bergamot polyphenols inhibit HMG-CoA reductase — the same enzyme targeted by pharmaceutical statin drugs — reducing the rate of hepatic cholesterol synthesis. Clinical trials have demonstrated dose-dependent reductions in LDL and triglycerides.

What it is

Berberine is a naturally occurring alkaloid found in several plants including Berberis and goldenseal. It is one of the most extensively researched botanical compounds for metabolic and cardiovascular support.

What it does

Berberine activates AMPK and upregulates LDL receptor expression in the liver — increasing the clearance of LDL cholesterol from circulation. It also supports healthy triglyceride levels and glucose metabolism.

What it is

Red Yeast Rice is produced by fermenting rice with Monascus purpureus yeast. This fermentation produces monacolin K — a compound identical to the pharmaceutical lovastatin.

What it does

Monacolin K inhibits HMG-CoA reductase, reducing hepatic cholesterol synthesis. Red yeast rice has been used in traditional Chinese medicine for centuries and has substantial clinical evidence for supporting healthy cholesterol levels.

What it is

Acetyl-L-Carnitine is an acetylated form of L-carnitine involved in fatty acid transport and metabolism. It shuttles fatty acids into mitochondria for energy production.

What it does

ALCAR supports healthy lipid metabolism by facilitating the transport and oxidation of fatty acids. It has been shown in research to support healthy HDL levels and triglyceride metabolism.

What it is

Myo-Inositol is involved in cellular signaling and lipid metabolism. It is a component of cell membranes and plays a role in insulin signal transduction.

What it does

Myo-Inositol supports healthy lipid metabolism and has been shown to improve lipid profiles in clinical research. It also supports the insulin sensitivity that influences how the body handles dietary fats.

What it is

Oleuropein is the primary bioactive polyphenol in olive leaves and oil — the compound most associated with the cardiovascular benefits of the Mediterranean diet.

What it does

Oleuropein protects LDL particles from oxidation — the process that makes LDL harmful to arterial walls. Oxidized LDL, not LDL itself, is most directly implicated in cardiovascular concerns.

What it is

DHA is a long-chain omega-3 fatty acid with documented effects on lipid metabolism and cardiovascular health.

What it does

DHA supports healthy triglyceride levels and has been shown to improve the size and density profile of LDL particles — shifting toward larger, less atherogenic particles.

What it is

EPA is an omega-3 fatty acid with potent effects on triglyceride metabolism and inflammatory balance in vascular tissue.

What it does

EPA has the most robust clinical evidence for triglyceride reduction among omega-3 fatty acids. It also supports healthy inflammatory balance in arterial walls and reduces platelet aggregation.